田原分子分光研究室 Molecular Spectroscopy Laboratory


Hydrogen bonds at model biological interfaces

Hydrogen bonds at model biological interfaces

Heterodyne-detected vibrational sum frequency generation (HD-VSFG) is applied to the investigation of hydrogen-bond structure at model biological interfaces, such as the surfactant/water and lipid/water interfaces. It is found that the “up” or “down” orientation of water molecules at these interfaces is dictated by the electric charges of hydrophilic head groups of surfactants and lipids. It is also found that the hydrogen-bond strengths of water at these charged monolayer interfaces are similar to that of bulk water. We further found that the hydrogen bond strength at the interface of a charged monolayer and salt solutions follows the Hofmeister series.
Nihonyanagi (J. Mondal, Adhikari, Sartin)

Fig. 1 Schematic drawing of Hofmeister series. Ions located in the left tend to salting- out proteins from solution while ions in the right induce salting-in.

Fig. 2. Schematic drawing of the model proposed in our study. (top) At positively charged surfactant interfaces, strongly hydrated fluoride counter ions do not directly adsorbed on the interface while weakly hydrated iodide directly adsorbed on the interface. The trend of contact adsorption is well correlated with Hofmeister series. (bottom) At negatively charged interfaces, counter cations do not form contact adsorption on the interface. It is revealed that the hydrogen bond strengths of the interfacial water molecules are correlated with Hofmeister series.